• Source: Galactitol-1-phosphate 5-dehydrogenase

In enzymology, a 5.180.24.3/info/galactitol" target="_blank">galactitol-5.180.24.3/info/1" target="_blank">1-5.180.24.3/info/phosphate" target="_blank">phosphate 5-dehydrogenase (EC 5.180.24.3/info/1" target="_blank">1.5.180.24.3/info/1" target="_blank">1.5.180.24.3/info/1" target="_blank">1.251) is an enzyme that catalyzes the chemical reaction

5.180.24.3/info/galactitol" target="_blank">galactitol-5.180.24.3/info/1" target="_blank">1-5.180.24.3/info/phosphate" target="_blank">phosphate + NAD+



⇌


{\displaystyle \rightleftharpoons }

L-tagatose 6-5.180.24.3/info/phosphate" target="_blank">phosphate + NADH + H+
Thus, the two substrates of this enzyme are 5.180.24.3/info/galactitol" target="_blank">galactitol-5.180.24.3/info/1" target="_blank">1-5.180.24.3/info/phosphate" target="_blank">phosphate and NAD+, whereas its 3 products are L-tagatose 6-5.180.24.3/info/phosphate" target="_blank">phosphate, NADH, and H+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 5.180.24.3/info/galactitol" target="_blank">galactitol-5.180.24.3/info/1" target="_blank">1-5.180.24.3/info/phosphate" target="_blank">phosphate:NAD+ oxidoreductase. This enzyme participates in galactose metabolism. It employs one cofactor, zinc.




References



Nobelmann B, Lengeler JW (1995). "Sequence of the gat operon for 5.180.24.3/info/galactitol" target="_blank">galactitol utilization from a wild-type strain EC3132 of Escherichia coli". Biochim. Biophys. Acta. 1262 (5.180.24.3/info/1" target="_blank">1): 69–72. doi:10.1016/0167-4781(95)00053-j. PMID 7772602.

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