- Source: Guanosine deaminase
In enzymology, a guanosine deaminase (EC 3.5.4.15) is an enzyme that catalyzes the chemical reaction
guanosine + H2O
⇌
{\displaystyle \rightleftharpoons }
xanthosine + NH3
Thus, the two substrates of this enzyme are guanosine and H2O, whereas its two products are xanthosine and NH3.
This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in cyclic amidines. The systematic name of this enzyme class is guanosine aminohydrolase. This enzyme is also called guanosine aminase.
References
Isihida Y, Shirafiji H, Kida M, Yoneda M (1969). "Studies on the guanosine degrading system in bacterial cell. III Preparation and properties of guanosine deaminase". Agric. Biol. Chem. 33: 384–390. doi:10.1080/00021369.1969.10859324.
Kata Kunci Pencarian:
- Guanosine deaminase
- ADAR
- Nucleic acid metabolism
- Guanine
- 2,5-Diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine
- Purine metabolism
- Adenosine monophosphate
- List of EC numbers (EC 3)
- Purine nucleoside phosphorylase deficiency
- Aciclovir
