• Source: Hematologic disease

Hematologic diseases are disorders which primarily affect the blood and blood-forming organs. Hematologic diseases include rare genetic disorders, anemia, HIV, sickle cell disease and complications from chemotherapy or transfusions.




Myeloid


Hemoglobinopathies (congenital abnormality of the hemoglobin molecule or of the rate of hemoglobin synthesis)
Sickle cell disease
Thalassemia
Methemoglobinemia
Anemias (lack of red blood cells or hemoglobin)
Iron-deficiency anemia
Megaloblastic anemia
Vitamin B12 deficiency
Pernicious anemia
Folate deficiency
Hemolytic anemias (destruction of red blood cells)
Genetic disorders of RBC membrane
Hereditary spherocytosis
Hereditary elliptocytosis
Congenital dyserythropoietic anemia
Genetic disorders of RBC metabolism
Glucose-6-phosphate dehydrogenase deficiency (G6PD)
Pyruvate kinase deficiency
Immune mediated hemolytic anemia (direct Coombs test is positive)
Autoimmune hemolytic anemia
Warm antibody autoimmune hemolytic anemia
Idiopathic
Systemic lupus erythematosus (SLE)
Evans syndrome (antiplatelet antibodies and hemolytic antibodies)
Cold autoimmune hemolytic anemia
Cold agglutinin disease
Paroxysmal cold hemoglobinuria (rare)
Infectious mononucleosis
Alloimmune hemolytic anemia
Hemolytic disease of the newborn (HDN)
Rh disease (Rh D)
ABO hemolytic disease of the newborn
Anti-Kell hemolytic disease of the newborn
Rhesus c hemolytic disease of the newborn
Rhesus E hemolytic disease of the newborn
Other blood group incompatibility (RhC, Rhe, Kid, Duffy, MN, P and others)
Drug induced immune mediated hemolytic anemia
Penicillin (high dose)
Methyldopa
Hemoglobinopathies (where these is an unstable or crystalline hemoglobin)
Paroxysmal nocturnal hemoglobinuria (rare acquired clonal disorder of red blood cell surface proteins)
Direct physical damage to RBCs
Microangiopathic hemolytic anemia
Secondary to artificial heart valve(s)
Aplastic anemia
Fanconi anemia
Diamond–Blackfan anemia (inherited pure red cell aplasia)
Acquired pure red cell aplasia
Decreased numbers of cells
Myelodysplastic syndrome
Myelofibrosis
Neutropenia (decrease in the number of neutrophils)
Agranulocytosis
Glanzmann's thrombasthenia
Thrombocytopenia (decrease in the number of platelets)
Idiopathic thrombocytopenic purpura (ITP)
Thrombotic thrombocytopenic purpura (TTP)
Heparin-induced thrombocytopenia (HIT)
Myeloproliferative disorders (Increased numbers of cells)
Polycythemia vera (increase in the number of cells in general)
Erythrocytosis (increase in the number of red blood cells)
Leukocytosis (increase in the number of white blood cells)
Thrombocytosis (increase in the number of platelets)
Myeloproliferative disorder
Transient myeloproliferative disease
Coagulopathies (disorders of bleeding and coagulation)
Thrombocytosis
Recurrent thrombosis
Disseminated intravascular coagulation
Disorders of clotting proteins
Hemophilia
Hemophilia A
Hemophilia B (also known as Christmas disease)
Hemophilia C
Von Willebrand disease
Disseminated intravascular coagulation
Protein S deficiency
Antiphospholipid syndrome
Disorders of platelets
Thrombocytopenia
Glanzmann's thrombasthenia
Wiskott–Aldrich syndrome




Hematological malignancies


Hematological malignancies
Lymphomas
Hodgkin's disease
Non-Hodgkin's lymphoma {includes the next five entries}
Burkitt's lymphoma
Anaplastic large cell lymphoma
Splenic marginal zone lymphoma
Hepatosplenic T-cell lymphoma
Angioimmunoblastic T-cell lymphoma (AILT)
Myelomas
Multiple myeloma
Waldenström macroglobulinemia
Plasmacytoma
Leukemias increased WBC
Acute lymphocytic leukemia (ALL)
Chronic lymphocytic leukemia (CLL){now included in theCLL/SCLL type NHL}
Acute myelogenous leukemia (AML)
Acute megakaryoblastic leukemia (AMKL), a sub-type of acute myelogenous leukemia
Chronic Idiopathic Myelofibrosis (MF)
Chronic myelogenous leukemia (CML)
T-cell prolymphocytic leukemia (T-PLL)
B-cell prolymphocytic leukemia (B-PLL)
Chronic neutrophilic leukemia (CNL)
Hairy cell leukemia (HCL)
T-cell large granular lymphocyte leukemia (T-LGL)
Aggressive NK-cell leukemia




Miscellaneous


Hemochromatosis
Asplenia
Hypersplenism
Gaucher's disease
Monoclonal gammopathy of undetermined significance
Hemophagocytic lymphohistiocytosis
Tempi syndrome




Hematological changes secondary to non-hematological disorders


Anemia of chronic disease
Infectious mononucleosis
AIDS
Malaria
Leishmaniasis




References






External links


https://web.archive.org/web/20100527085120/http://hematologic.niddk.nih.gov/info/index.htm

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