- Source: HGSNAT
Heparan-α-glucosaminide N-acetyltransferase (also called "acetyl-CoA:heparan-α-D-glucosaminide N-acetyltransferase" and "acetyl-CoA:alpha-glucosaminide N-acetyltransferase") is an enzyme that in humans is encoded by the HGSNAT gene.
In enzymology, this enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. It is catalysed in the chemical reaction:
acetyl-CoA + heparan sulfate α-D-glucosaminide
⇌
{\displaystyle \rightleftharpoons }
CoA + heparan sulfate N-acetyl-α-D-glucosaminide
This enzyme participates in glycosaminoglycan degradation and glycan structures degradation. Mutations in the gene encoding this enzyme cause mucopolysaccharidosis IIIC.
References
Further reading
Kata Kunci Pencarian:
- Daftar gen penyandi protein pada manusia/2
- HGSNAT
- Sanfilippo syndrome
- Mucopolysaccharidosis
- List of human protein-coding genes 2
- List of genetic disorders
- Chromosome 8
- N-acetyltransferase
- Uncharacterized protein C15orf32
- List of OMIM disorder codes
