- Source: HNRNPLL
Heterogeneous nuclear ribonucleoprotein L-like is a protein that in humans is encoded by the HNRNPLL gene.
Function
HNRNPLL is a master regulator of activation-induced alternative splicing in T cells. In particular, it alters splicing of CD45 (PTPRC; MIM 151460), a tyrosine phosphatase essential for T-cell development and activation.
References
Further reading
This article incorporates text from the United States National Library of Medicine, which is in the public domain.