- Source: Hydroxyacylglutathione hydrolase
The enzyme hydroxyacylglutathione hydrolase (EC 3.1.2.6, systematic name = S-(2-hydroxyacyl)glutathione hydrolase) catalyzes the following reaction:
S-(2-hydroxyacyl)glutathione + H2O = glutathione + a 2-hydroxy carboxylate
This enzyme belongs to the family of hydrolases, specifically the class of thioester lyases. It is commonly known as glyoxalase II. It participates in pyruvate metabolism.
References
Ball JC, Vander Jagt DL (1979). "Purification of S-2-hydroxyacylglutathione hydrolase (glyoxalase II) from rat erythrocytes". Anal. Biochem. 98 (2): 472–7. doi:10.1016/0003-2697(79)90169-6. PMID 496013.
