- Source: InaD-like protein
InaD-like protein is a protein that in humans is encoded by the PATJ gene.
Function
This gene encodes a protein with multiple PDZ domains. PDZ domains mediate protein-protein interactions, and proteins with multiple PDZ domains often organize multimeric complexes at the plasma membrane. This protein localizes to tight junctions and to the apical membrane of epithelial cells. A similar protein in Drosophila is a scaffolding protein which tethers several members of a multimeric signaling complex in photoreceptors.
Interactions
INADL has been shown to interact with MPP5.
References
Further reading
External links
INADL human gene location in the UCSC Genome Browser.
INADL human gene details in the UCSC Genome Browser.
Overview of all the structural information available in the PDB for UniProt: Q8NI35 (InaD-like protein) at the PDBe-KB.