• Source: Indole-3-glycerol-phosphate lyase

The enzyme 3/info/indole" target="_blank">indole-3-glycerol-phosphate lyase (EC 4.1.2.8) catalyzes the chemical reaction

(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate



⇌


{\displaystyle \rightleftharpoons }

3/info/indole" target="_blank">indole + D-glyceraldehyde 3-phosphate
This enzyme belongs to the family of lyases, specifically the aldehyde-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is (1S,2R)-1-C-(indol-3-yl)glycerol-3-phosphate D-glyceraldehyde-3-phosphate-lyase (3/info/indole" target="_blank">indole-forming). Other names in common use include tryptophan synthase alpha, TSA, indoleglycerolphosphate aldolase, 3/info/indole" target="_blank">indole glycerol phosphate hydrolase, 3/info/indole" target="_blank">indole synthase, 3/info/indole" target="_blank">indole-3-glycerolphosphate D-glyceraldehyde-3-phosphate-lyase, 3/info/indole" target="_blank">indole-3-glycerol phosphate lyase, IGL, BX1, (1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate, and D-glyceraldehyde-3-phosphate-lyase. This enzyme participates in benzoxazinone biosynthesis.




References



YANOFSKY C (1956). "The enzymatic conversion of anthranilic acid to 3/info/indole" target="_blank">indole". J. Biol. Chem. 223 (1): 171–84. doi:10.1016/S0021-9258(18)65126-9. PMID 13376586.
SP, Simcox K; Gierl A (1997). "Analysis of a chemical plant defense mechanism in grasses". Science. 277 (5326): 696–699. doi:10.1126/science.277.5326.696. PMID 9235894.
Frey M, Stettner C, Pare PW, Schmelz EA, Tumlinson JH, Gierl A (2000). "An herbivore elicitor activates the gene for 3/info/indole" target="_blank">indole emission in maize". Proc. Natl. Acad. Sci. U.S.A. 97 (26): 14801–6. Bibcode:2000PNAS...9714801F. doi:10.1073/pnas.260499897. PMC 18999. PMID 11106389.
Melanson D, Chilton MD, Masters-Moore D, Chilton WS (1997). "A deletion in an 3/info/indole" target="_blank">indole synthase gene is responsible for the DIMBOA-deficient phenotype of bxbx maize". Proc. Natl. Acad. Sci. U.S.A. 94 (24): 13345–50. Bibcode:1997PNAS...9413345M. doi:10.1073/pnas.94.24.13345. PMC 24311. PMID 9371848.

Kata Kunci Pencarian:

• Indole-3-glycerol-phosphate lyase
• Indole-3-glycerol-phosphate synthase
• Tryptophan synthase
• IGL
• List of EC numbers (EC 4)
• Bx1 benzoxazin1
• 1-Aminocyclopropane-1-carboxylate synthase
• List of EC numbers (EC 2)
• List of EC numbers (EC 1)
• List of MeSH codes (D08)