- Source: KLK8
Kallikrein-8 is a protein that in humans is encoded by the KLK8 gene.
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Alternate splicing of this gene results in four transcript variants encoding four different isoforms. The isoforms exhibit distinct patterns of expression that suggest roles in brain plasticity and ovarian cancer.
References
Further reading
External links
The MEROPS online database for peptidases and their inhibitors: S01.244
Kata Kunci Pencarian:
- Daftar gen penyandi protein pada manusia/2
- KLK8
- Kallikrein
- List of human protein-coding genes 2
- Lamellar bodies
- Kallikrein 8
