- Source: L-olivosyl-oleandolide 3-O-methyltransferase
3/info/l" target="_blank">L-3/info/olivosyl" target="_blank">olivosyl-3/info/oleandolide" target="_blank">oleandolide 3-O-methyltransferase (EC 2.1.1.239, OleY) is an enzyme with systematic name S-adenosyl-3/info/l" target="_blank">L-methionine:3/info/l" target="_blank">L-3/info/olivosyl" target="_blank">olivosyl-3/info/oleandolide" target="_blank">oleandolide B 3-O-methyltransferase. This enzyme catalyses the following chemical reaction
S-adenosyl-3/info/l" target="_blank">L-methionine + 3/info/l" target="_blank">L-3/info/olivosyl" target="_blank">olivosyl-3/info/oleandolide" target="_blank">oleandolide
⇌
{\displaystyle \rightleftharpoons }
S-adenosyl-3/info/l" target="_blank">L-homocysteine + 3/info/l" target="_blank">L-oleandrosyl-3/info/oleandolide" target="_blank">oleandolide
The enzyme is involved in the biosynthesis of the macrolide antibiotic oleandomycin in Streptomyces antibioticus.
References
External links
3/info/l" target="_blank">L-3/info/olivosyl" target="_blank">olivosyl-3/info/oleandolide" target="_blank">oleandolide+3-O-methyltransferase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)