- Source: Leukotriene receptor
The leukotriene (LT) receptors are G protein-coupled receptors that bind and are activated by the leukotrienes. They include the following proteins:
Leukotriene B4 receptors (BLTRs) – bind to and are activated by LTB4:
BLT1 (Leukotriene B4 receptor 1) – LTB4R
BLT2 (Leukotriene B4 receptor 2) – LTB4R2
Cysteinyl leukotriene receptors (CysLTRs) – bind to and are activated by LTC4, LTD4, and LTE4:
CysLT1 (Cysteinyl leukotriene receptor 1) – CYSLTR1
CysLT2 (Cysteinyl leukotriene receptor 2) – CYSLTR2
The recently elucidated CysLTE, represented by GPR99/OXGR1, may constitute a third CysLTR.
See also
Eicosanoid receptor
Oxoeicosanoid receptor
Prostaglandin receptor
Thromboxane receptor
References
External links
IUPHAR GPCR Database – Leukotriene receptors
Leukotriene+Receptors at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
Kata Kunci Pencarian:
- Rinitis alergi
- Asma
- Antagonis reseptor leukotriena
- Leukotriene
- Antileukotriene
- Leukotriene receptor
- Cysteinyl leukotriene receptor 1
- Montelukast
- Cysteinyl leukotriene receptor 2
- Zafirlukast
- Hives
- Leukotriene B4 receptor
- Cysteinyl leukotriene receptor
