• Source: LMX1B

LIM homeobox transcription factor 1-beta, also known as LMX1B, is a protein which in humans is encoded by the LMX1B gene.




Function


LMX1B is a LIM homeobox transcription factor which plays a central role in dorso-ventral patterning of the vertebrate limb.




Clinical significance


Loss-of-function mutations in the LMX1B gene are associated with Nail-patella syndrome.




References






Further reading






External links


GeneReviews/NIH/NCBI/UW entry on Nail-Patella Syndrome
LIM+homeobox+transcription+factor+1+beta at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

Kata Kunci Pencarian:

• Daftar gen penyandi protein pada manusia/2
• LMX1B
• Nail–patella syndrome
• Kozak consensus sequence
• Homeobox
• Metencephalon
• Limb development
• Campomelic dysplasia
• List of human protein-coding genes 2
• List of human transcription factors
• Pitt–Hopkins syndrome