• Source: Long-chain-enoyl-CoA hydratase

The enzyme long-chain-enoyl-CoA hydratase (EC 4.2.1.74) catalyzes the chemical reaction

(3S)-3-hydroxyacyl-CoA



⇌


{\displaystyle \rightleftharpoons }

trans-2-enoyl-CoA + H2O
This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. The systematic name of this enzyme class is long-chain-(3S)-3-hydroxyacyl-CoA hydro-lyase. This enzyme is also called long-chain enoyl coenzyme A hydratase. This enzyme participates in fatty acid elongation in mitochondria and fatty acid metabolism.




References



Fong JC, Schulz H (1977). "Purification and properties of pig heart crotonase and the presence of short chain and long chain enoyl coenzyme A hydratases in pig and guinea pig tissues". J. Biol. Chem. 252 (2): 542–7. PMID 833142.
Schulz H (1974). "Long chain enoyl coenzyme A hydratase from pig heart". J. Biol. Chem. 249 (9): 2704–9. PMID 4828315.

Kata Kunci Pencarian:

• Long-chain-enoyl-CoA hydratase
• Enoyl-CoA hydratase
• Enoyl CoA isomerase
• HADHA
• HADHB
• Methylglutaconyl-CoA hydratase
• Beta oxidation
• HSD17B4
• Mitochondrial trifunctional protein deficiency
• Fatty acid metabolism