• Source: LPP (gene)

Lipoma-preferred partner is a protein that in humans is encoded by the LPP gene.




Function


Lipoma-preferred partner is a subfamily of LIM domain proteins that are characterized by an N-terminal proline rich region and three C-terminal LIM domains. The encoded protein localizes to the cell periphery in focal adhesions and may be involved in cell-cell adhesion and cell motility. This protein also shuttles through the nucleus and may function as a transcriptional co-activator. This gene is located at the junction of certain disease related chromosomal translocations which result in the expression of fusion proteins that may promote tumor growth.




References






Further reading



This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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