• Source: Manjula Reddy

Manjula Reddy (born 1965) is an Indian bacterial geneticist. She is the chief scientist at the Centre for Cellular and Molecular Biology in Hyderabad, India. In 2019, she won the Infosys Prize in Life Sciences for her work on bacterial cell wall structure and synthesis. She is a Fellow of the Telangana Academy of Sciences and the Indian Academy of Sciences.




Education and career


Manjula Reddy earned her PhD from the Centre for Cellular and Molecular Biology in 2002. She started her own lab at the institution in 2007.




Research


Manjula Reddy conducts research on bacterial cell walls.
She identified a novel "spacemaker" enzyme encoded by the open reading frame called MepK in Escherichia coli. She found that this enzyme hydrolyses certain cross-links in peptidoglycan thereby allowing the bacterial cell wall to expand. She aims to develop novel antimicrobials that can target the peptidoglycan synthesis pathway. She uses the model organisms Mycobacterium smegmatis and Escherichia coli.
She was part of the team of scientists who patented the process for identifying mutagens and anti-mutagens. This process was patented from 1999 to 2018 in the United States. The other scientists in the team were Jayaraman Gowrishankar and Shanti M. Bharatan.




Awards and honors


Infosys Prize in Life Sciences (2019)
Fellow of the Indian Academy of Sciences (2020)
Fellow of the Telangana Academy of Sciences
Editorial board member of the Journal of Bacteriology




Personal life


She has stated in an interview that her father, Mohan Reddy, and her mother were supportive of her career as a scientist. She is married to a cardiologist and has two sons.




Selected publications



Chodisetti, Pavan Kumar, and Manjula Reddy. "Peptidoglycan hydrolase of an unusual cross-link cleavage specificity contributes to bacterial cell wall synthesis." Proceedings of the National Academy of Sciences 116.16 (2019): 7825-7830.
Singh, Santosh Kumar, et al. "Regulated proteolysis of a cross-link–specific peptidoglycan hydrolase contributes to bacterial morphogenesis." Proceedings of the National Academy of Sciences 112.35 (2015): 10956-10961.
Reddy, Manjula. "Role of FtsEX in cell division of Escherichia coli: viability of ftsEX mutants is dependent on functional SufI or high osmotic strength." Journal of bacteriology 189.1 (2007): 98-108.




References

Kata Kunci Pencarian:

• Alluri Seetharama Raju (film 1974)
• Daftar pemeran film perempuan India
• Rani Mukerji
• Orange (film 2010)
• Penghargaan Filmfare untuk Film Terbaik – Telugu
• Krishna (pemeran)
• Penghargaan Nandi untuk Film Fitur Terbaik
• Daftar penerima penghargaan Padma Shri (2010–2019)
• Filmografi Trisha
• Manjula Reddy
• List of Indian scientists
• Anita Reddy
• Infosys Prize
• List of South Indian film families
• Chandler Unified School District
• Maa Annayya Bangaram
• Osmania Medical College
• Ramesh Babu
• Centre for Cellular and Molecular Biology