• Source: Mannose receptor C-type 1

Mannose receptor C-type 1 is a protein that in humans is encoded by the MRC1 gene.




Function


The recognition of complex carbohydrate structures on glycoproteins is an important part of several biological processes, including cell-cell recognition, serum glycoprotein turnover, and neutralization of pathogens. The protein encoded by this gene is a type I membrane receptor that mediates the endocytosis of glycoproteins by macrophages. The protein has been shown to bind high-mannose structures on the surface of potentially pathogenic viruses, bacteria, and fungi so that they can be neutralized by phagocytic engulfment.




References






Further reading



This article incorporates text from the United States National Library of Medicine, which is in the public domain.

Kata Kunci Pencarian:

• Mannose receptor C-type 1
• Mannose receptor
• Pattern recognition receptor
• Mannose 6-phosphate receptor
• Mannose
• Insulin-like growth factor 2 receptor
• Collagen receptor
• Phagocytosis
• Fibronectin type II domain
• Mincle receptor