• Source: Methyl 4-iodobenzoate

Methyl 4-iodobenzoate, or methyl p-iodobenzoate, is an organic compound with the formula IC6H4COOCH3. It is the methyl ester of 4-iodobenzoic acid, or may also be viewed as an iodinated derivative of methyl benzoate.




Preparation


Methyl 4-iodobenzoate may be prepared by the Fischer esterification of 4-iodobenzoic acid with methanol.




Reactions



The aryl-iodide functionality of methyl 4-iodobenzoate may undergo coupling reactions, such as a symmetrical Sonogashira coupling with trimethylsilylacetylene (with the TMSA deprotected to acetylene in situ) to form dimethyl 4,4'-(ethyne-1,2-diyl)dibenzoate.




References

Kata Kunci Pencarian:

• Methyl 4-iodobenzoate
• 4-Iodobenzoic acid
• Aryl halide
• List of compounds with carbon number 8
• Sonogashira coupling
• Photolabile protecting group
• List of MeSH codes (D02)