- Source: Mexican Federal Highway 54
- Jaringan Nasional
- California
- Modesto, California
- Mexican Federal Highway 54
- Mexican Federal Highway 85
- Mexican Federal Highway 15D
- List of Mexican Federal Highways
- Mexican Federal Highway 57
- Mexican Federal Highway 2
- Mexican Federal Highway 1
- List of highways numbered 54
- Mexican Federal Highway 160D
- Mexican Federal Highway 57D
Federal Highway 54 (Carretera Federal 54) Fed. 54 is a free (libre) part of the federal highways corridors (los corredores carreteros federales) and connects Ciudad Mier, Tamaulipas, to Colima City.
The highway joins Fed. 15 and Fed. 80 in the southwest part of Guadalajara. For 148 km (92 mi), the Fed. 54 designation is substituted by Fed. 54D from Acatlán de Juárez, Jalisco to Ciudad Guzmán, a toll road.
Across the southern Mexican Plateau, Fed. 54 connects Zacatecas in the southwest to Monterrey in the northeast at Fed. 57.