- Source: ML domain
The MD-2-related lipid-recognition (ML) domain is implicated in lipid recognition, particularly in the recognition of pathogen related products. It has an immunoglobulin-like beta-sandwich fold similar to that of immunoglobulin E-set domains. This domain is present in the following proteins:
Epididymal secretory protein E1 (also known as Niemann-Pick C2 protein), which is known to bind cholesterol. Niemann-Pick disease type C2 is a fatal hereditary disease characterised by accumulation of low-density lipoprotein-derived cholesterol in lysosomes.
House dust mite allergen proteins such as Der f 2 from Dermatophagoides farinae and Der p 2 from Dermatophagoides pteronyssinus.
Human proteins containing this domain
LY86; LY96; MMD-1;
References
Kata Kunci Pencarian:
- Nama domain
- Ranah internet tingkat teratas
- .ml
- .id
- Mali
- .co
- .sg
- .dz
- .dd
- .cn
- .ml
- ML domain
- ML
- ML (programming language)
- .so
- Country code top-level domain
- Three-domain system
- PackML
- Systems modeling language
- .cf