- Source: Mphahlele
Mphahlele is a surname of South African origin. Notable people with this name include:
Es'kia Mphahlele (1919–2008), South African writer
Letlapa Mphahlele (born 1960), South African politician
Ramahlwe Mphahlele (born 1990), South African association football player
Ryan Mphahlele (born 1998), South African runner
Segopotje Mphahlele (born 1968), South African judge