• Source: NEIL2

Endonuclease VIII-like 2 is an enzyme that in humans is encoded by the NEIL2 gene.
NEIL2 belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the associated lyase reaction (Bandaru et al., 2002)[supplied by OMIM]




See also


NEIL1
NEIL3
OGG1
NTHL1




References






Further reading

Kata Kunci Pencarian:

• NEIL2
• DNA glycosylase
• NEIL1
• List of human protein-coding genes 3
• NEIL3
• DNA-(apurinic or apyrimidinic site) lyase
• NTHL1
• SMUG1
• Halystina globulus