• Source: Neutrophil cytosolic factor 2

Neutrophil cytosol factor 2 is a protein that in humans is encoded by the NCF2 gene.




Function


This gene encodes neutrophil cytosolic factor 2, the 67-kilodalton cytosolic subunit of the multi-protein complex known as NADPH oxidase found in neutrophils. This oxidase produces a burst of superoxide which is delivered to the lumen of the neutrophil phagosome. Mutations in this gene, as well as in other NADPH oxidase subunits, can result in chronic granulomatous disease.




References






Further reading






External links


Overview of all the structural information available in the PDB for UniProt: P19878 (Neutrophil cytosol factor 2) at the PDBe-KB.

Kata Kunci Pencarian:

• Inflamasom
• Neutrophil cytosolic factor 2
• Neutrophil cytosolic factor 4
• Neutrophil cytosolic factor 1
• Tetratricopeptide repeat
• Neutrophil
• Neutrophil extracellular traps
• Coagulation
• Tetratricopeptide repeat domain 16 isoform 1
• Respiratory burst
• Interleukin 8