• Source: O-methylated flavonoid

The O-methylated flavonoids or methoxyflavonoids are flavonoids with methylations on hydroxyl groups (methoxy bonds). O-methylation has an effect on the solubility of flavonoids.




Enzymes


O-methylated flavonoids formation implies the presence of specific O-methyltransferase (OMT) enzymes which accept a variety of substrates. Those enzymes mediate the O-methylation on a specific hydroxyl group, like on 4' (example in Catharanthus roseus) or 3' (example in rice) positions. Those positions can be ortho, meta, para and there can be a special 3-O-methyltransferase for the 3-OH position. Calamondin orange (Citrus mitis) exhibits all of those activities.




= Plant enzymes

=
Apigenin 4'-O-methyltransferase
8-hydroxyquercetin 8-O-methyltransferase
Isoflavone 4'-O-methyltransferase
Isoflavone 7-O-methyltransferase
Isoliquiritigenin 2'-O-methyltransferase
Isoorientin 3'-O-methyltransferase
Kaempferol 4'-O-methyltransferase
Luteolin O-methyltransferase
Methylquercetagetin 6-O-methyltransferase
3-methylquercetin 7-O-methyltransferase
Myricetin O-methyltransferase
Quercetin 3-O-methyltransferase
Vitexin 2"-O-rhamnoside 7-O-methyltransferase




= Animal enzyme

=
Catechol-O-methyl transferase




O-methylated anthocyanidins


5-Desoxy-malvidin
Capensinidin
Europinidin
Hirsutidin
Malvidin
Peonidin
Petunidin
Pulchellidin
Rosinidin




O-methylated flavanols


Meciadanol (3-O'methyl catechin)




O-methylated flavanones


Hesperetin
Homoeriodictyol
Isosakuranetin
Sakuranetin
Sterubin




O-methylated flavanonols


Dihydrokaempferide




O-methylated flavonols


of kaempferol

Kaempferide
of myricetin

Annulatin
Combretol
Europetin
Laricitrin (3'-O-Dimethylmyricetin)
5-O-methylmyricetin
Syringetin (3',5'-O-Dimethylmyricetin)
of quercetin

Ayanin
Azaleatin
Isorhamnetin
Ombuin
Pachypodol
Retusin (quercetin-3,7,3',4'-tetramethyl ether)
Rhamnazin
Rhamnetin
Tamarixetin
other

Eupatolitin
Natsudaidain




O-methylated flavones


Acacetin
Chrysoeriol
Diosmetin
Nepetin
Nobiletin
Oroxylin-A
Sinensetin
Tangeritin
Thevetiaflavone
Wogonin




O-methylated isoflavones


Biochanin A
Calycosin
Formononetin
Glycitein
Irigenin
5-O-methylgenistein
Pratensein
Prunetin
Psi-tectorigenin
Retusin
Tectorigenin




See also


C-methylated flavonoid




References

Kata Kunci Pencarian:

• Metilasi
• O-methylated flavonoid
• C-methylated flavonoid
• Methylation
• Dalbergia retusa
• Isosakuranetin
• Kerria japonica
• Europinidin
• Nobiletin
• Methoxy group
• Hesperetin