• Source: Oscar Hertwig

Oscar Hertwig (21 April 1849 in Friedberg – 25 October 1922 in Berlin) was a German embryologist and zoologist known for his research in developmental biology and evolution. Hertwig is credited as the first man to observe sexual reproduction by looking at the cells of sea urchins under the microscope.




Biography


Hertwig was the elder brother of zoologist-professor Richard Hertwig (1850–1937). The Hertwig brothers were the most eminent scholars of Ernst Haeckel (and Carl Gegenbaur) from the University of Jena. They were independent of Haeckel's philosophical speculations but took his ideas in a positive way to widen their concepts in zoology. Initially, between 1879 and 1883, they performed embryological studies, especially on the theory of the coelom (1881), the fluid-filled body cavity. These problems were based on the phylogenetic theorems of Haeckel, i.e. the biogenic theory (German = biogenetisches Grundgesetz), and the "gastraea theory".
Within 10 years, the two brothers moved apart to the north and south of Germany.
Oscar Hertwig later became a professor of anatomy in 1888 in Berlin; however, Richard Hertwig had moved 3 years prior, becoming a professor of zoology in Munich from 1885 to 1925, at Ludwig Maximilian University, where he served the last 40 years of his 50-year career as a professor at 4 universities.
Hertwig was a leader in the field of comparative and causal animal-developmental history. He also wrote a leading textbook. By studying sea urchins he proved that fertilization occurs due to the fusion of a sperm and egg cell. He recognized the role of the cell nucleus during inheritance and chromosome reduction during meiosis: in 1876, he published his findings that fertilization includes the penetration of a spermatozoon into an egg cell. Hermann Fol also observed this in the same year.
Hertwig's experiments with frog eggs revealed the 'long axis rule', or Hertwig rule. According to this rule, cell divides along its long axis.
In 1885 Hertwig wrote that nuclein (later called nucleic acid) is the substance responsible not only for fertilization but also for the transmission of hereditary characteristics. This early suggestion was proven correct much later in 1944 by the Avery–MacLeod–McCarty experiment which showed that this is indeed the role of the nucleic acid DNA.
While Hertwig was interested in developmental biology and evolution, he was opposed to chance as assumed in Charles Darwin´s theory. His most important theoretical book was: "Das Werden der Organismen, eine Widerlegung der Darwinschen Zufallslehre" (Jena, 1916) (translation: "The Origin of Organisms – a Refutation of Darwin's Theory of Chance").
Hertwig was elected a member of the Royal Swedish Academy of Sciences in 1903.
Hertwig is known as Oscar Hedwig in the book "Who discovered what when" by David Ellyard. A history of the discovery of fertilization for mammals including scientists like Hertwig and other workers is given by the book "The Mammalian Egg" by Austin.




Works


Die Elemente der Entwicklungslehre des Menschen und der Wirbeltiere : Anleitung und Repetitorium für Studierende und Ärzte. Fischer, Jena 5th ed. 1915 Digital edition by the University and State Library Düsseldorf
Das Problem der Befruchtung und der Isotropie des Eies. Eine Theorie der Vererbung. Jenaische Zeitschrift fur Naturwissenschaft 18, 276–318.




See also


Epigenetics
Evolution – concepts and history of evolutionary thought




References






Other sources


Gill, P (1990), "Nature and nurture.", Med. J. Aust., vol. 152, no. 7 (published Apr 2, 1990), p. 386, doi:10.5694/j.1326-5377.1990.tb125235.x, PMID 2093819, S2CID 8081330
Weindling, P (1980), "Social concepts in anatomy: theories of the cell state of Oscar Hertwig (1849–1922) and Wilhelm Waldeyer (1836–1921).", The Society for the Social History of Medicine Bulletin, vol. 26 (published Jun 1980), pp. 15–7, PMID 11610800
Gras, N; Verchere, M; Santoro, J P (1975), "[The Oscar Hertwig centenary]", Revue d'Odonto-stomatologie, vol. 4, no. 2, pp. 135–40, PMID 1103253
Churchill, F B (1970), "Hertwig, Weismann, and the meaning of reduction division circa 1890.", Isis; an International Review Devoted to the History of Science and Its Cultural Influences, vol. 61, no. 4, pp. 429–57, doi:10.1086/350680, PMID 4942056, S2CID 46321527
Cremer, T. 1985. Von der Zellenlehre zur Chromosomentheorie. Springer Vlg., Heidelberg. This German book can be downloaded here [1].
Krafft, F., and A. Meyer-Abich (ed.). 1970. Große Naturwissenschaftler – Biographisches Lexikon. Fischer Bücherei GmbH, Frankfurt a. M. & Hamburg.
Mol. Cell. Biol.-lecture, Heidelberg, D.-H. Lankenau. Early to recent key-discoveries: From Germline Theory to Modern Gene Modification.
Weindling, Paul. 1991. Darwinism and Social Darwinism in Imperial Germany: The Contribution of the Cell Biologist Oscar Hertwig (1849–1922). Forschungen zur Medizin- und Biologiegeschichte vol. 3, (Stuttgart: G. Fischer in association with Akademie der Wissenschaften und der Literatur Mainz, 1991).




External links



Works by Oscar Hertwig at Project Gutenberg
Works by or about Oscar Hertwig at the Internet Archive
The first chapters of O. Hertwig's book Lehrbuch der Entwicklungsgeschichte des Menschen und der Wirbeltiere (1906) are available online here

Kata Kunci Pencarian:

• Vitalisme
• Oscar Hertwig
• Richard Hertwig
• Hertwig
• Human fertilization
• Leonor Michaelis
• Friedberg, Hesse
• Landsmannschaft (Studentenverbindung)
• Pronucleus
• Ornithoprion
• Index of biology articles