- Source: OTX1
Homeobox protein OTX1 is a protein that in humans is encoded by the OTX1 gene.
Function
This gene encodes a member of the bicoid sub-family of homeodomain-containing transcription factors. The encoded protein acts as a transcription factor and may play a role in brain and sensory organ development. The Otx gene is active in the region of the first gill arch, which is related to the upper and lower jaw and two of the bones of the ear. A similar protein in mice is required for proper brain and sensory organ development and can cause epilepsy.
References
Further reading
External links
OTX1+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
Kata Kunci Pencarian:
- OTX1
- Metencephalon
- List of human transcription factors
- Thalamus
- Homeobox
- Ear
- Utriculosaccular duct
- Orthodenticle
- List of human protein-coding genes 3
- ETFDH