• Source: Papilloma

A papilloma (plural papillomas or papillomata) (papillo- + -oma) is a benign epithelial tumor growing exophytically (outwardly projecting) in nipple-like and often finger-like fronds. In this context, papilla refers to the projection created by the tumor, not a tumor on an already existing papilla (such as the nipple).
When used without context, it frequently refers to infections (squamous cell papilloma) caused by human papillomavirus (HPV), such as warts. Human papillomavirus infection is a major cause of cervical cancer, vulvar cancer, vaginal cancer, penis cancer, anal cancer, and HPV-positive oropharyngeal cancers. Most viral warts are caused by human papillomavirus infection (HPV), of which there are nearly 200 distinct human papillomaviruses (HPVs), and many HPV types are carcinogenic. There are, however, a number of other conditions that cause papilloma, as well as many cases in which there is no known cause.




Signs and symptoms



A benign papillomatous tumor is derived from epithelium, with cauliflower-like projections that arise from the mucosal surface.
It may appear white or normal colored. It may be pedunculated or sessile. The average size is between 1–5 cm. Neither sex is significantly more likely to develop them. The most common site is the palate-uvula area followed by tongue and lips. Durations range from weeks to 10 years.




Presence of HPV


Immunoperoxidase stains have identified antigens of the human papillomavirus (HPV) types 6 and 11 in approximately 50% of cases of squamous cell papilloma.




Prognosis


There is no evidence that papillomas are premalignant.




Differential diagnosis


Intraoral verruca vulgaris,
Condyloma acuminatum, and
Focal epithelial hyperplasia.
Note: differentiation is done accurately by microscopic examination only.




Treatment


With conservative surgical excision, recurrence is rare.




See also


Skin tag
Inverted papilloma
Squamous cell papilloma
Urothelial papilloma
Intraductal papilloma of breast
Wart
Genital wart
Plantar wart
Papillomavirus
Human papillomavirus




References






External links



Choroid Plexus Papilloma - Palmer, Cheryl Ann and Daniel Keith Harrison; EMedicine; Jun 5, 2008

Kata Kunci Pencarian:

• Kutil
• Papiloma
• Seks oral
• Tumor
• Vaksin HPV
• Kondiloma Akuminata
• Serviks
• Tumor jinak
• Kanker anus
• Jaringan saraf
• Papilloma
• Intraductal papilloma
• Squamous cell papilloma
• Human papillomavirus infection
• Shope papilloma virus
• Urothelial papilloma
• Inverted papilloma
• Ductal papilloma
• Choroid plexus papilloma
• Verrucous cyst