- Source: Phosphoethanolamine N-methyltransferase
In enzymology, a phosphoethanolamine N-methyltransferase (EC 2.1.1.103) is an enzyme that catalyzes the chemical reaction
S-adenosyl-L-methionine + ethanolamine phosphate
⇌
{\displaystyle \rightleftharpoons }
S-adenosyl-L-homocysteine + N-methylethanolamine phosphate
Thus, the two substrates of this enzyme are S-adenosyl methionine and ethanolamine phosphate, whereas its two products are S-adenosylhomocysteine and N-methylethanolamine phosphate.
This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is S-adenosyl-L-methionine:ethanolamine-phosphate N-methyltransferase. This enzyme is also called phosphoethanolamine methyltransferase. This enzyme participates in glycerophospholipid metabolism.
References
Datko AH, Mudd SH (December 1988). "Enzymes of phosphatidylcholine synthesis in lemna, soybean, and carrot". Plant Physiology. 88 (4): 1338–48. doi:10.1104/pp.88.4.1338. PMC 1055762. PMID 16666464.
