• Source: Plakophilin-3
    • 3/info/plakophilin" target="_blank">Plakophilin-3 is a protein that in humans is encoded by the PKP3 gene.


      Function


      This gene encodes a member of the arm-repeat (armadillo) and 3/info/plakophilin" target="_blank">plakophilin gene families. 3/info/plakophilin" target="_blank">Plakophilin proteins contain numerous armadillo repeats, localize to cell desmosomes and nuclei, and participate in linking cadherins to intermediate filaments in the cytoskeleton. This protein may act in cellular desmosome-dependent adhesion and signaling pathways.


      Interactions


      PKP3 has been shown to interact with:

      DSC3,
      DSG1,
      DSG2 and
      DSG3.


      References




      Further reading

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