- Source: Propanamide
Propanamide has the chemical formula CH3CH2C=O(NH2). It is the amide of propanoic acid.
This organic compound is a mono-substituted amide. Organic compounds of the amide group can react in many different organic processes to form other useful compounds for synthesis.
Preparation
Propanamide can be prepared by the condensation reaction between urea and propanoic acid:
(
NH
2
)
2
CO
+
2
CH
3
CH
2
COOH
⟶
CH
3
CH
2
CO
(
NH
2
)
+
H
2
O
+
CO
2
{\displaystyle {\ce {(NH2)2CO + 2CH3CH2COOH -> CH3CH2CO(NH2) + H2O + CO2}}}
or by the dehydration of ammonium propionate:
(
NH
4
)
CH
3
CH
2
COO
⟶
CH
3
CH
2
CONH
2
+
H
2
O
{\displaystyle {\ce {(NH4)CH3CH2COO -> CH3CH2CONH2 + H2O}}}
Reactions
Propanamide being an amide can participate in a Hofmann rearrangement to produce ethylamine gas.