- Source: Psammoma body
A psammoma body is a round collection of calcium, seen microscopically. The term is derived from Greek άμμος (ámmos) 'sand'.
Cause
Psammoma bodies are associated with the papillary (nipple-like) histomorphology and are thought to arise from,
Infarction and calcification of papillae tips.
Calcification of intralymphatic tumor thrombi.
Association with lesions
Psammoma bodies are commonly seen in certain tumors such as:
Papillary thyroid carcinoma
Papillary renal cell carcinoma
Ovarian papillary serous cystadenoma and cystadenocarcinoma
Endometrial adenocarcinomas (papillary serous carcinoma ~3%-4%)
Meningiomas, in the central nervous system
Peritoneal and pleural mesothelioma
Somatostatinoma (pancreas)
Prolactinoma of the pituitary
Glucagonoma
Micropapillary subtype of lung adenocarcinoma
Benign lesions
Psammoma bodies may be seen in:
Endosalpingiosis
Psammomatous melanotic schwannoma
Melanocytic nevus
Appearance
Psammoma bodies usually have a laminar appearance, are circular, acellular and basophilic.
References
External links
Slides:
Meningioma
Thyroid cancer
Endometriosis (peritoneum)
Video of psammoma bodies in meningioma
Kata Kunci Pencarian:
- Psammoma body
- Meningioma
- Calcification
- Corpora arenacea
- Uterine serous carcinoma
- Serous tumour
- Noninvasive follicular thyroid neoplasm with papillary-like nuclear features
- Somatostatinoma
- Thyroid neoplasm
- Papillary thyroid cancer