- Source: Pyridine-2-carbaldehyde
Pyridine-2-carbaldehyde, also called 2-formylpyridine, is an organic compound with the formula NC5H4CHO. It is one of three isomeric pyridinaldehydes. The other isomers are pyridine-3-carboxaldehyde and pyridine-4-carboxaldehyde.
Pyridine-2-carbaldehyde is a colorless oily liquid with a distinctive odor. Older samples are often brown-colored owing to impurities. It serves as a precursor to other compounds of interest in coordination chemistry and pharmaceuticals. Pyridine aldehydes are typically prepared by oxidation of the hydroxymethyl- or methylpyridines.
Reactions and uses
The drug pralidoxime can be produced from 2-formylpyridine.
The aldehyde functional group is subject to nucleophilic attack, specifically by amines to form Schiff bases, which serve as bidentate ligands. Iminopyridine complexes can be remarkably robust.
References
Kata Kunci Pencarian:
- Pyridine-2-carbaldehyde
- Pyridine-3-carbaldehyde
- Pyridine-4-carbaldehyde
- Pralidoxime
- Nucleic acid analogue
- Base pair
- Aldehyde
- Pyridoxal
- Xenobiology
- Dakin oxidation
