• Source: RBX1

RING-box protein 1 is a protein that in humans is encoded by the RBX1 gene.




Function


This gene encodes an evolutionarily conserved protein that interacts with cullins. The protein plays a unique role in the ubiquitination reaction by heterodimerizing with cullin-1 to catalyze ubiquitin polymerization. It also may be involved in the regulation of protein turn-over.




Interactions


RBX1 has been shown to interact with:




References






Further reading

Kata Kunci Pencarian:

• RBX1
• SCF complex
• Ubiquitin ligase
• Molecular glue
• Cullin
• CUL1
• Ning Zheng
• 22q13 deletion syndrome
• Von Hippel–Lindau tumor suppressor
• Chromosome 22