• Source: RGS11

Regulator of G-protein signaling 11 is a protein that in humans is encoded by the RGS11 gene.
The protein encoded by this gene belongs to the RGS (regulator of G protein signaling) family. Members of the RGS family act as GTPase-activating proteins on the alpha subunits of heterotrimeric, signal-transducing G proteins. This protein inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified.




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Further reading

Kata Kunci Pencarian:

• RGS11
• List of human protein-coding genes 3
• GGL domain
• Regulator of G protein signaling
• David Siderovski
• RGS7
• RGS6
• GNB5