• Source: Richard Gallo

      • Richard L. Gallo is an American dermatologist who is a Distinguished Professor and founding Chairman of Dermatology at the University of California, San Diego. His research accomplishments as a physician-scientist include discovery of antimicrobial peptides in mammalian skin, establishing new links between innate immunity and skin diseases such as atopic dermatitis and rosacea, and defining the functions of the skin microbiome in host immune defense.


      Education


      Gallo did his undergraduate studies at the University of Chicago, earned his MD and PhD at the University of Rochester, interned in Pediatrics at Johns Hopkins Hospital, was a Dermatology resident at Harvard Medical School and was a postdoctoral fellow at Harvard University under the supervision of Merton Bernfield'


      Research


      Gallo studies how humans interact with the environment and protect themselves from infection. He discovered that antimicrobial peptides are present in mammalian skin by demonstrating that cathelicidin antimicrobial peptides(Cathelicidins) are present during wound repair. Subsequent work from his laboratory used molecular techniques to produce a knock out mouse that has shown how cathelicidin antimicrobials protect against infection in several organs including the skin. By using a wide variety of biochemical and genetic tools his work has also shown that other antimicrobial peptides and elements of innate immunity such as Toll-like receptors and Hyaluronan influence human health. His work has translated into a new understanding of the cause of rosacea, a finding with immediate therapeutic implications. Most recently his research has defined biochemical mechanisms through which Vitamin D and the normal skin microflora Microbiome can control immune responses. These latest findings have advanced understanding of the Hygiene hypothesis, Atopic Dermatitis and Rosacea. His analysis of the function of the human skin microbiome is leading discovery of new therapeutic approaches to disease by discovering molecules from bacteria on the skin that can be used for drugs.
      Several press releases and scientific publications have reported his discoveries.


      Awards and honors


      1990- AMA/Archives of Dermatology Young Investigator Award
      2002- Stern Endowment for Dermatology Research, Nobel Lectureship- Karolinska Institute
      2003- Elected American Society for Clinical Investigation
      2006- Montagna Award, Society for Investigative Dermatology
      2007- CE.R.I.E.S. Award
      2009- Stiefel Lectureship, Dermatology Foundation; Blank Lectureship, SID; Mertz award, Duhring Lectureship-U Penn
      2010- Elected Association of American Physicians
      2011- Rene’Touraine Award-European Society Dermatologic Research
      2012- Sulzberger Award- American Academy of Dermatology, Lerner lecture-Yale, Gilliam Lecture-UT Southwestern
      2013- Rook Oration, British Academy of Dermatology
      2014- Elected American Society for Microbiology, Dohi Lectureship and Honorary membership in Japanese Dermatology Association
      2015- Haynes Lectureship, Harvard Medical School, Rodan-Fields Lectureship, Stanford University
      2017- Elected elected as a fellow of the American Association for the Advancement of Science, Newcomer Lectureship- UCLA, Lifetime Achievement Award- Manchester UK
      2018- Named Irma Gigli Endowed Chair of Dermatology, UCSD
      2019- NIH MERIT award
      2022- Rothman Award, Society for Investigative Dermatology
      2022- David Martin Carter Award, American Skin Association
      2023- Van Scott Lectureship and Frost Award, American Academy of Dermatology
      2023- Elected to the National Academy of Medicine


      References

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