- Source: Ricinine nitrilase
In enzymology, a ricinine nitrilase (EC 3.5.5.2) is an enzyme that catalyzes the chemical reaction
ricinine + 2 H2O
⇌
{\displaystyle \rightleftharpoons }
3-carboxy-4-methoxy-N-methyl-2-pyridone + NH3
Thus, the two substrates of this enzyme are ricinine and H2O, whereas its two products are 3-carboxy-4-methoxy-N-methyl-2-pyridone and NH3.
This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in nitriles. The systematic name of this enzyme class is ricinine aminohydrolase. This enzyme participates in nitrogen metabolism.
References
ROBINSON WG, HOOK RH (1964). "Ricinine Nitrilase. I. Reaction Product and Substrate Specificity". J. Biol. Chem. 239: 4257–62. PMID 14247679.
HOOK RH, ROBINSON WG (1964). "Ricinine Nitrilase. Ii. Purification and Properties". J. Biol. Chem. 239: 4263–7. PMID 14247680.
Pace HC, Brenner C (2001). "The nitrilase superfamily: classification, structure and function". Genome Biol. 2 (1): REVIEWS0001. doi:10.1186/gb-2001-2-1-reviews0001. PMC 150437. PMID 11380987.
