• Source: Rostral interstitial nucleus of medial longitudinal fasciculus

The rostral interstitial nucleus of medial longitudinal fasciculus (riMLF) is a collection of neurons in the medial longitudinal fasciculus in the midbrain. It is responsible for mediating vertical conjugate eye movements (vertical gaze): 458.e1  and vertical saccades.: 122  It mostly projects efferents to the ipsilateral oculomotor and trochlear nuclei.: 458.e1 
To mediate downgaze, it projects efferents to the ipsilateral oculomotor nucleus and trochlear nucleus; mediate upgaze,: 777-778  it projects efferents to the contralateral aforementioned nuclei: 122  through the posterior commissure.: 777-778 
It is one of the accessory oculomotor nuclei.: 156 




Anatomy






= Structure

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The riMLF is a wing-shaped nucleus.: 458.e1 
The riMLF contains two populations of neurons: excitatory burst neurons mediating vertical gaze/saccades, as well as omnipause neurons which are functionally similar to those mediating horizontal gaze.: 1464.e17 




= Relations

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It is situated at the caudal extremity of the mesencephalon at its junction with the telencephalon,: 156  at the level of the superior colliculus. It is situated dorsal to the rostral extremity of the red nucleus, and rostral to the interstitial nucleus of Cajal.: 458.e1 




Clinical significance


Lesions of the riMLF may impair vertical gaze completely, or predominately impair downgaze.: 778  Lesions of the posterior commissure meanwhile disrupt upgaze.: 1464.e17 




See also


Interstitial nucleus of Cajal - another structure involved in vertical gaze (including torsional gaze and gaze holding, but not saccades).
Paramedian pontine reticular formation - the horizontal gaze center.




References

Kata Kunci Pencarian:

• Rostral interstitial nucleus of medial longitudinal fasciculus
• Medial longitudinal fasciculus
• Parinaud's syndrome
• Interstitial nucleus of Cajal
• List of regions in the human brain
• Paramedian pontine reticular formation
• Gaze (physiology)
• Accessory oculomotor nuclei
• Conjugate eye movement
• Sense of balance