• Source: RS134-49

RS134-49 is a tetrahydropyridine derivative related to psychedelic tryptamines which acts as a 5-HT2A receptor agonist, with a 5-HT2A Ki of 11.5nM and an EC50 of 22nM. It is a biased agonist selective for activation of the Gq coupled signalling pathway with weaker activation of the β-arrestin 2 coupled pathway, but shows a more balanced profile than related compounds such as (R)-69.




See also


4-Methyl-α-methyltryptamine
4-Methyl-α-ethyltryptamine
CP-94253
RU-24,969
SN-22
VU6067416




References

Kata Kunci Pencarian:

• RS134-49
• C14H16N2
• 4-Methyl-α-methyltryptamine
• VU6067416
• List of miscellaneous 5HT2A agonists
• 4-Methyl-α-ethyltryptamine
• BRL-54443
• Bank of Punjab
• RU-24,969