- Source: Saccharopolyspora spinosa
Saccharopolyspora spinosa is a species of actinobacterium first isolated from soil in a rum still in an abandoned sugar mill on the Virgin Islands. It was discovered and described by researchers Mertz and Yao while collecting specimens to be screened for novel antibiotics. It develops aerial, pale, yellowish pink hyphae and bears long chains of spores encased in spiny spore sheaths. It can also reproduce by fragmentation in an aqueous environment. Its type strain is A83543.1 (= NRRL 18395).
Saccharopolyspora spinosa is the source of a family of insecticidal compounds called spinosyns. They act as neurotoxins by activation of nicotinic acetylcholine receptors in insects. The insecticide Spinetoram is composed of two synthetic derivatives of spinosyns.
See also
Spinosad
References
Further reading
Pan, Y.; Yang, X.; Li, J.; Zhang, R.; Hu, Y.; Zhou, Y.; Wang, J.; Zhu, B. (2011). "Genome Sequence of the Spinosyns-Producing Bacterium Saccharopolyspora spinosa NRRL 18395". Journal of Bacteriology. 193 (12): 3150–3151. doi:10.1128/JB.00344-11. ISSN 0021-9193. PMC 3133185. PMID 21478350.
Kim, Hak Joong; White-Phillip, Jess A.; Ogasawara, Yasushi; Shin, Nara; Isiorho, Eta A.; Liu, Hung-wen (2010). "Biosynthesis of Spinosyn in Saccharopolyspora spinosa: Synthesis of Permethylated Rhamnose and Characterization of the Functions of SpnH, SpnI, and SpnK". Journal of the American Chemical Society. 132 (9): 2901–2903. doi:10.1021/ja910223x. ISSN 0002-7863. PMC 2832084. PMID 20158237.
Jin, Zhi-hua; Wu, Jian-ping; Zhang, Yuan; Cheng, Xiu; Yang, Li-rong; Cen, Pei-lin (2006). "Improvement of spinosad producing Saccharopolyspora spinosa by rational screening". Journal of Zhejiang University Science A. 7 (S2): 366–370. doi:10.1631/jzus.2006.AS0366. ISSN 1009-3095. S2CID 122475979.
External links
"Saccharopolyspora spinosa". The Encyclopedia of Life.
Type strain of Saccharopolyspora spinosa at BacDive - the Bacterial Diversity Metadatabase
Kata Kunci Pencarian:
- Saccharopolyspora spinosa
- Spinosad
- Saccharopolyspora
- S. spinosa
- Saccharopolyspora phatthalungensis
- Spinetoram
