• Source: SAM-IV riboswitch
  • SAM-IV riboswitches are a kind of riboswitch that specifically binds S-adenosylmethionine (SAM), a cofactor used in many methylation reactions. Originally identified by bioinformatics, SAM-IV riboswitches are largely confined to the Actinomycetales, an order of Bacteria. Conserved features of SAM-IV riboswitch and experiments imply that they probably share a similar SAM-binding site to another class of SAM-binding riboswitches called SAM-I riboswitches. However, the scaffolds of these two types of riboswitch appear to be quite distinct. The structural relationship between these riboswitch types has been studied.


    See also


    SAM-I riboswitch
    SAM-II riboswitch
    SAM-III riboswitch
    SAM-V riboswitch
    SAM-VI riboswitch


    References




    External links



    Page for SAM-IV_riboswitch at Rfam

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