• Source: Sarcosine/dimethylglycine N-methyltransferase

Sarcosine/dimethylglycine N-methyltransferase (EC 2.1.1.157, ApDMT, sarcosine-dimethylglycine methyltransferase, SDMT, sarcosine dimethylglycine N-methyltransferase, S-adenosyl-L-methionine:N,N-dimethylglycine N-methyltransferase) is an enzyme with systematic name S-adenosyl-L-methionine:sarcosine(or N,N-dimethylglycine) N-methyltransferase (N,N-dimethylglycine(or betaine)-forming). This enzyme catalyses the following chemical reaction

2 S-adenosyl-L-methionine + sarcosine



⇌


{\displaystyle \rightleftharpoons }

2 S-adenosyl-L-homocysteine + betaine (overall reaction)
(1a) S-adenosyl-L-methionine + sarcosine



⇌


{\displaystyle \rightleftharpoons }

S-adenosyl-L-homocysteine + N,N-dimethylglycine
(1b) S-adenosyl-L-methionine + N,N-dimethylglycine



⇌


{\displaystyle \rightleftharpoons }

S-adenosyl-L-homocysteine + betaine
This enzyme participates in biosynthesis of betaine from glycine in cyanobacterium Aphanocthece halophytica.




References






External links


Sarcosine/dimethylglycine+N-methyltransferase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

Kata Kunci Pencarian:

• Sarcosine/dimethylglycine N-methyltransferase
• Glycine/sarcosine/dimethylglycine N-methyltransferase
• S-adenosyl-L-methionine:N,N-dimethylglycine N-methyltransferase
• Glycine/sarcosine N-methyltransferase
• Sarcosine dehydrogenase
• List of EC numbers (EC 2)
• Creatine
• Glycocyamine
• Hemantane
• Methylene blue