- Source: Small nucleolar RNA U2-19
In molecular biology, the Small nucleolar RNA U2-19 is a non-coding RNA (ncRNA) molecule that functions in the modification of other small nuclear RNAs (snRNAs). This type of modifying RNA is usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and is also often referred to as a guide RNA.
snoRNA U2-19 belongs to the C/D box class of snoRNAs which contain the conserved sequence motifs known as the C box (UGAUGA) and the D box (CUGA). Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs. snoRNA U2-19 directs 2'-O-methylation of U2 spliceosomal RNA G-19.
References
External links
Page for Small nucleolar RNA U2-19 at Rfam
Kata Kunci Pencarian:
- Small nucleolar RNA U2-19
- Small nucleolar RNA
- Small nucleolar RNA U2-30
- Non-coding RNA
- Small Cajal body-specific RNA
- Nucleic acid sequence
- SnRNP
- Pseudouridine
- Minor spliceosome
- LSm