• Source: Stephen Crohn

      • Stephen Lyon Crohn (September 5, 1946 – August 23, 2013), also known as "the man who can't catch AIDS", was a man notable for a genetic mutation that caused him to be immune to AIDS. He was a great-nephew of Burrill Bernard Crohn, for whom Crohn's disease is named.
      Crohn had the Δ32 mutation on the CCR5 receptor, a protein on the surface of white blood cells that is involved in the immune system and serves as an access route for many forms of HIV to enter and infect host cells. This mutation rendered him effectively immune to many forms of HIV.


      Death


      Crohn committed suicide by a drug overdose on oxycodone and benzodiazepines at the age of 66.


      See also


      Timothy Ray Brown
      Adam Castillejo
      Innate resistance to HIV
      Long-term nonprogressor
      HIV/AIDS research


      References




      External links


      Video and text from a PBS documentary about Stephen Crohn and the discovery of CCR5

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