- Source: Stercobilinogen
Stercobilinogen (fecal urobilinogen) is a chemical created by bacteria in the gut. It is made of broken-down hemoglobin. It is further processed to become the chemical that gives feces its brown color.
Bilirubin is a pigment that results from the breakdown of the heme portion of hemoglobin. The liver conjugates bilirubin, making it water-soluble; and the conjugated form is then excreted in urine as urobilinogen and in the feces as stercobilinogen. Urobilinogen / stercobilinogen is colourless and is further oxidised to stercobilin which imparts colour to feces. Darkening of feces upon standing in air is due to the oxidation of residual urobilinogens to urobilins. In the intestine, bilirubin is converted by bacteria to stercobilinogen. Stercobilinogen is absorbed and excreted by either the liver or the kidney.
References
Harpers illustrated biochemistry 28th Ed.
Harrison’s principles of internal medicine 20th Ed.
Kata Kunci Pencarian:
- Stercobilinogen
- Urobilinogen
- Stercobilin
- Bilirubin
- Bilirubinuria
- Jaundice
- Heme
- Neonatal jaundice
- Urine test strip