• Source: T-shaped uterus

A t-shaped uterus is a type of uterine malformation wherein the uterus is shaped resembling the letter T. This is typically observed in DES-exposed women. It is recognised in the ESHRE/ESGE classification, and is associated with failed implantation, increased risk of ectopic pregnancy, miscarriage and preterm delivery. There is a surgical procedure to correct the malformation.




Causes


The T-shaped malformation is commonly associated with in-utero exposure to diethylstilbestrol (the so-called "DES daughters"). It is also presented congenitally.




Diagnosis


Women are often diagnosed with this condition after several failed pregnancies, proceeded by exploratory diagnostic procedures, such as magnetic resonance, sonography, and particularly hysterosalpingography. In such studies, a widening of the interstitial and isthmus of uterine tube is observed, as well as constrictions or narrowing of the uterus as a whole, especially the lower and lateral portions, hence the "t" denomination. The uterus might be simultaneously reduced in volume, and other abnormalities might be concomitantly present.




Prognosis


Although fertility is impaired, T-shaped uterus sufferers can bear children. However, they carry a greater risk of complications, such as miscarriages, reduced fertility and preterm births, both before and after any treatment.
The current surgical procedure to treat this malformation, termed a hysteroscopic correction or metroplasty, is undertaken by performing a lateral incision of the uterine walls, and can return the organ to a normal morphology, while improving the patient's former reproductive performance. It is considered a low-risk procedure, and can also improve term delivery rate by up to 10-fold, as long as the endometrium is considered to be in good condition. However, risks after the procedure include placenta accreta, Asherman's syndrome and severe haemorrhage.




See also


Vaginal adenosis




References






Further reading


Kaufman RH (1982). "Structural changes of the genital tract associated with in utero exposure to diethylstilbestrol". Obstet Gynecol Annu. 11: 187–202. PMID 7110645.
Goldberg, Jeffrey M; Falcone, Tommaso (1999). "Effect of diethylstilbestrol on reproductive function". Fertility and Sterility. 72 (1): 1–7. doi:10.1016/S0015-0282(99)00153-3. ISSN 0015-0282. PMID 10428139.
KALTFMANL, RAYMOND H., MD ERVIN ADAM, and Gary L. Binder. "Upper genital tract changes and pregnancy outcome in offspring exposed in utero to diethylstilbestrol." (1980).
Lin PC (2004). "Reproductive outcomes in women with uterine anomalies". J Womens Health (Larchmt). 13 (1): 33–9. doi:10.1089/154099904322836438. PMID 15006276.

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• Diethylstilbestrol
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