- Source: Transcription factor DP
In molecular biology, transcription factor DP (Dimerization Partner) is a family of proteins which function as transcription factors.
DP forms a heterodimer with E2F and regulates genes involved in cell cycle progression. The transcriptional activity of E2F is inhibited by the retinoblastoma protein which binds to the E2F-DP heterodimer and negatively regulates the G1-S transition.
See also
E2F
TFDP1
TFDP2
References
Kata Kunci Pencarian:
- BRCA1
- Reseptor vitamin D
- Transcription factor DP
- TFDP2
- TFDP1
- Transcription factor II F
- E2F
- Cis-regulatory element
- Gene expression
- NF-κB
- Enhancer (genetics)
- Regulation of gene expression