• Source: Trimethoprim/sulfadoxine

Trimethoprim/sulfadoxine, sold under the brand name Trimidox, is an antibacterial agent that is used in cattle and swine to prevent and treat infections by both gram-negative and gram-positive bacteria.




Veterinary uses


Trimethoprim/sulfadoxine is used in the treatment of swine and cattle, including dairy cattle, beef cattle and veal.
In cattle, it is used to treat:

Respiratory tract infections such as bovine pneumonia pasteurellosis (shipping fever)
Alimentary tract infections such as salmonellosis and both enteric and septicaemic colibacillosis
Other infections such as pododermatitis (foot rot) and septicaemias
In swine, it is used to treat:

Respiratory tract infections such as bacterial pneumonias
Alimentary tract infections such as post-weaning scours and colibacillosis
Other infections such as bacterial arthritis and mastitis-metritis-agalactia syndrome in sows.




= Contraindications

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Trimethoprim/sulfadoxine is contraindicated in cattle or swine that show marked liver parenchymal damage or blood dyscrasias, or those with a history of sulfonamide sensitivity.
Milk from an animal treated with trimethoprim/sulfadoxine must not be consumed for at least 96 hours following the most recent treatment; treated animals must not be slaughtered for use in food for at least ten days after the last treatment.




References

Kata Kunci Pencarian:

• Trimethoprim/sulfadoxine
• WHO Model List of Essential Medicines for Children
• List of veterinary drugs
• ATC code J01
• WHO Model List of Essential Medicines
• Pyrimethamine
• Prontosil
• Atovaquone/proguanil
• Dapsone
• Primaquine