- Source: Trimethylamine-oxide aldolase
The enzyme trimethylamine-oxide aldolase (EC 4.1.2.32) catalyzes the chemical reaction
trimethylamine N-oxide
⇌
{\displaystyle \rightleftharpoons }
dimethylamine + formaldehyde
This enzyme belongs to the family of lyases, specifically the aldehyde-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is trimethylamine-N-oxide formaldehyde-lyase (dimethylamine-forming). Other names in common use include trimethylamine N-oxide formaldehyde-lyase, trimethylamine N-oxide aldolase, trimethylamine N-oxide demethylase, and trimethylamine-N-oxide formaldehyde-lyase. This enzyme participates in methane metabolism.
References
Large PJ (1971). "Non-oxidative demethylation of trimethylamine N-oxide by Pseudomonas aminovorans". FEBS Lett. 18 (2): 297–300. doi:10.1016/0014-5793(71)80470-2. PMID 11946146.
Myers PA, Zatman LJ (1971). "The metabolism of trimethylamine N-oxide by Bacillus PM6". Biochem. J. 121 (1): 10P. PMC 1176517. PMID 5116524.