• Source: Tris(2-pyridylmethyl)amine

Tris(2-pyridylmethyl)amine (abbreviated TPMA or TPA) is an organic compound with the formula (C5H4NCH2)3N. It is a tertiary amine with three picolyl substituents. It is a white solid that is soluble in polar organic solvents. It is a ligand in coordination chemistry.
The ligand is prepared by the alkylation of 2-picolylamine by picolyl chloride:

2 C5H4NCH2Cl + C5H4NCH2NH2 → (C5H4NCH2)3N + 2 HCl
TPMA is a tripodal ligand, often used to simulate the coordination environment within some proteins. It is also used as a copper ligand in ATRP.




Related ligands


dipicolylamine, an intermediate in the synthesis of TPMA.
2-picolylamine, a bidentate ligand, also known as aminomethylpyridine.




References

Kata Kunci Pencarian:

• Tris(2-pyridylmethyl)amine
• 2-Picolylamine
• TPA
• Tripodal ligand
• Tetradentate ligand
• Dipicolylamine
• White–Chen catalyst
• Liquid–liquid extraction
• Jenny Y. Yang
• Nitrate chlorides