- Source: UDP-glucuronate decarboxylase
The enzyme UDP-glucuronate decarboxylase (EC 4.1.1.35) catalyzes the chemical reaction
UDP-D-glucuronate
⇌
{\displaystyle \rightleftharpoons }
UDP-D-xylose + CO2
This enzyme belongs to the family of lyases, specifically the carboxy-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is UDP-D-glucuronate carboxy-lyase (UDP-D-xylose-forming). Other names in common use include uridine-diphosphoglucuronate decarboxylase, and UDP-D-glucuronate carboxy-lyase. This enzyme participates in starch and sucrose metabolism and nucleotide sugars metabolism. It employs one cofactor, NAD+.
Structural studies
As of late 2007, two structures have been solved for this class of enzymes, with PDB accession codes 2B69 and 2BLL.
References
Ankel H, Feingold DS (1965). "Biosynthesis of uridine diphosphate D-xylose. 1. Uridine diphosphate glucuronate carboxy-lyase of wheat germ". Biochemistry. 4 (11): 2468–2475. doi:10.1021/bi00887a028.
Kata Kunci Pencarian:
- UDP-glucuronate decarboxylase
- UXS1
- UDP-glucuronic acid dehydrogenase
- List of EC numbers (EC 4)
- List of EC numbers (EC 1)
- List of EC numbers (EC 2)
