- Source: V-set and immunoglobulin domain containing 4
V-set and immunoglobulin domain containing 4 is a protein that in humans is encoded by the VSIG4 gene.
Function
This gene encodes a v-set and immunoglobulin-domain containing protein that is structurally related to the B7 family of immune regulatory proteins. The encoded protein may be a negative regulator of T-cell responses. This protein is also a receptor for the complement component 3 fragments C3b and iC3b. Alternate splicing results in multiple transcript variants.
References
Further reading
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
Kata Kunci Pencarian:
- V-set and immunoglobulin domain containing 4
- Immunoglobulin V-set domain
- Immunoglobulin C2-set domain
- Immunoglobulin superfamily
- Immunoglobulin C1-set domain
- Immunoglobulin I-set domain
- Immunoglobulin heavy chain
- Protein domain
- Complement receptor of the immunoglobulin family
- Titin